2008

• Yamaguchi K., Whitlock N, Liggett J, Legendre A, Fry M, and Baek SJ . (2008) Molecular Characterization of Canine Nonsteroidal Anti-inflammatory Drug-activated Gene ( NAG-1 ). Vet J . In Press.

• Lee SH, Cekanova M, and Baek SJ. (2008) Multiple mechanisms are involved in 6-gingerol-induced cell cycle arrest and apoptosis in human colorectal cancer cells. Mol Carcinog. In Press.

• Cekanova M, Li, X, Yuan J, Kim, K, and Baek SJ . (2008) Gene alteration by PPARgamma ligands. Int J Oncol . In Press

• Kim HJ, Park SH, Park SY, Moon UY, Lee BD, Yoon SH, Lee JG, Baek SJ , Yoon JH. (2008) Epigallocatechin-3-gallate inhibits interleukin-1beta-induced MUC5AC gene expression and MUC5AC secretion in normal human nasal epithelial cells. J Nutr Biochem . In Press.

2007

• Fernando R, Foster JS, Bible A, Strom A, Pestell RG, Rao M, Saxton A, Baek SJ , Yamaguchi K, Donnell R, Cekanova M, Wimalasena J (2007) Breast cancer cell proliferation is inhibited by BAD: Regulation of cyclin D1. J Biol Chem. Sep. 282(39):28864-28873.

• Cho KN, Sukthanka M, Lee SH, Yoon JH, and Baek SJ . (2007) ECG induces ATF3 expression in human colorectal cancer cells. Eur J Cancer . Nov. 43(16):2404-2412.

• Rojsanga P, Sukthanka M, Wandee G, and Baek SJ (2007) Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF-3 expression in human colorectal cancer cells. Can Lett . Dec. 258(2):230-240.

2006

• Yamaguchi K, Liggett JL, Kim NC, and Baek SJ (2006) Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells. Oncol Rep. Jan 15(1):275-281.

• Baek SJ, and Eling TE (2006) Changes in gene expression contribute to cancer prevention by COX inhibitors. Prog Lipid Res. Jan. 45(1):1-16.

• Yamaguchi K, Lee SH, Kim JS, Wimalasena J, Kitajima S, and Baek SJ (2006) Activating transcription factor 3 and early growth response-1 are the novel targets of LY294002 in a PI3K independent manner. Cancer Res. Feb 66(4): 2376-2384.

• Wu WW, Wang G, Baek SJ, and Shen RF (2006) Comparative Study of Three Proteomic Quantitative Methods, DIGE, cICAT, and iTRAQ, Using 2D Gel- or LC-MALDI TOF/TOF. J Proteome Res. Mar 5(3):651-658.

• Lee SH, Yamaguchi K, Kim JS, Eling TE, Safe S, Park Y, and Baek SJ (2006) Conjugated linoleic acid stimulates NAG-1 expression by isomer specific manner. Carcinogenesis. May 27(5):972-981.

• Yamaguchi K, Lee SH, Eling TE, and Baek SJ. (2006) A novel peroxisome proliferator-activated receptor g ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells. Mol Cancer Ther. May 5(5):1352-1361.

• Lambert JR, Kelly JA, Shim M, Huffer WE, Nordeen, SK, Baek SJ, Eling TE, and Lucia SM. (2006) Prostate derived factor in human prostate cancer cells: Gene induction by vitamin D via a p53 dependent mechanism and inhibition of PCa cell growth. J Cell Physiol. Jun. 208(3):566-574.

• Martinez J, Sali T, Okazaki R, Hollingshead M, Hose C, Monks A, Baek SJ, Walker N, and Eling TE (2006) Drug induced up-regulation of NAG-1 attenuates tumor formation. J Pharmacol Exp Ther. Aug 318(2):899-906.

• Baek SJ, Okazaki R, Lee SH, Martinez J, Kim JS, Yamaguchi K, Mishina Y, Martin D, Shoieb A, McEntee M, and Eling TE (2006) NAG-1/MIC-1/GDF-15 Over-Expression in Transgenic Mice Suppresses Colorectal Neoplasia. Gastroenterology. In Press.

• Eling TE, Baek SJ , Shim M, and Lee CH. (2006) NSAID activated gene (NAG-1), a modulator of tumorigenesis. J Biochem Mol Biol. Nov. 39(6):649-655.

• Lim YC, Lee SH, Song MH, Yamaguchi K, Yoon JH, Choi EC, and Baek SJ (2006) Growth inhibition and apoptosis by (-)-epicatechin gallate are mediated by cyclin D1 suppression in head and neck squamous carcinoma cells. Eur J Cancer. In Press.

 

2005

• Baek SJ, Kim JS, Moore SM, Lee SH, Martinez J, and Eling TE. (2005) Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an anti-tumorigenic protein. Mol Pharmacol. Feb. 67(2): 356-364.

• Cho KN, Choi JY, Kim CH, Baek SJ, Chung KC, Moon UY, Kim KS, Lee WJ, Koo JS, and Yoon JH (2005) Prostaglandin E2 Induces MUC8 Gene Expression via a Mechanism Involving ERK MAPK/RSK1/CREB Activation in Human Airway Epithelial Cells. J Biol Chem. Feb 280(8): 6676-6681

• Lee SH, Kim JS, Yamaguchi K, Eling TE, and Baek SJ (2005) Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independnet manner. Biochem Biophys Res Commun. Mar. 328(1):63-69.

• Kim JS, Baek SJ, Sali T, and Eling TE (2005) The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15 Mol Cancer Ther. Mar. 4(3):487-493.

• Kim JH, Yamaguchi K, Lee SH, Tithof PK, Sayler GS, Yoon JH, and Baek SJ. (2005) Evaluation of polycyclic aromatic hydrocarbons in the activation of early growth response-1 and peroxisome proliferator activated receptors. Toxicol Sci. May 85(1):585-593.

• Kim JS, Baek SJ, Bottone FG, Sali T and Eling TE. (2005) Over-expression of 15-lipoxygenase-1 induces growth arrest via phosphorylation of p53 in human colorectal cancer cells. Mol Cancer Res. Sep 3(9):511-7.

• Yoon JH, and Baek SJ (2005) Molecular Targets of Dietary Polyphenols with anti-inflammatory Properties. Yonsei Med J. Oct. 46(5):585-596.

• Chintharlapalli S, Papineni S, Baek SJ, Liu S, and Safe S. (2005) 1,1-Bis(3’-indolyl)-1-(p-substitutedphenyl)methanes Activate peroxisome proliferators-activated receptor g in HCT-116 colon cancer cells but decreased cell survival through receptor-independent activation of NAG-1. Mol Pharmacol. Dec 68(6):1782-1792.

 

2004

• Baek SJ, Kim J-S, Nixon JB, DiAugustine RP, and Eling TE. (2004) Expression of NAG-1, a TGF-β superfamily member, by troglitazone requires the early growth response gene Egr-1. J Biol Chem. Feb, 279(8):6883-6892.

• Yamaguchi K, Lee SH, Eling TE, and Baek SJ (2004) Identification of Nonsteroidal Anti-Inflammatory Drug-activated gene (NAG-1) as a Novel Downstream Target of Phosphatidylinositol 3-Kinase/AKT/GSK3β pathway. J Biol Chem. Nov 279(48): 49617-49623.

• Martinez JM, Baek SJ, Mays DM, Tithof PK, Eling TE, Walker NJ. (2004) EGR-1 Is a Novel Target for AhR Agonists in Human Lung Epithelial Cells. Toxicol Sci. Dec, 82(2):429-435.

• Jain AK, Moore SM, Yamaguchi K, Eling TE, and Baek SJ. (2004) Selective NSAIDs Induce Thymosin β-4 and Alter Actin Cytoskeletal Organization in Human Colorectal Cancer Cells. J Pharmacol Exp Ther. Dec. 311(3):885-891.

• Kim KS, Yoon JH, Kim JK, Baek SJ, Eling TE, Lee WJ, Ryu JH, Lee JG, Lee JH, Yoo JB (2004). Cyclooxygenase inhibitors induce apoptosis in oral cavity cancer cells by increased expression of nonsteroidal anti-inflammatory drug-activated gene. Biochem Biophys Res Commun. Dec. 325(4):1298-1303.

• Fry MM, Liggett JL, and Baek SJ. (2004) Molecular cloning and expression of canine hepcidin. Vet Clin Pathol. Dec. 33(4):223-227.

• Baek SJ, Kim JS, Jackson FR, Eling TE, McEntee MF, and Lee SH. (2004) Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis, Dec. 25(12):2425-2432.

 

2003

• Newman D, Sakaue M, Koo JS, Kim KS, Baek SJ, Eling TE, and Jetten AM. (2003). Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids. Mol Pharmacol. Mar, 63(3):557-64.

• Baek SJ, Wilson L, Hsi L, and Eling TE (2003). Troglitazone, a Peroxisome Proliferator-activated Receptor gamma (PPARgamma) Ligand, Selectively Induces the Early Growth Response-1 Gene Independently of PPARgamma. A NOVEL MECHANISM FOR ITS ANTI-TUMORIGENIC ACTIVITY. J Biol Chem. Feb, 278(8):5845-5853.

• Nixon JB, Kamitani H, Baek SJ, and Eling TE (2003) Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. Prostaglandins Leukot Essent Fatty Acids. May, 68(5):323-330.

• Wilson L, Baek SJ, and Eling TE (2003) Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) is induced by genistein through the expression of p53 in colorectal cancer cells. Int J Cancer. Jul, 105(6):747-753

• Lee CH, Jang YS, Her SJ, Moon YM, Baek SJ, and Eling TE. (2003) Nordihydroguiaretic acid, the antioxidant, inhibits TGF-b activity through the inhibition of Smad signaling pathway. Exp.Cell Res. Oct, 289(2):335-341

• Kim KS, Shin JH, Baek SJ, Yoon JH. (2003) Expression of Non-steroidal Anti-inflammatory Drug-activated Gene-1 in Human Nasal Mucosa and Cultured Nasal Epithelial Cells: A Preliminary Investigation. Acta Oto-Laryngol, Oct 123(7):857-861

 

2002

• Baek SJ, Wilson L, and Eling TE (2002). Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53. Carcinogenesis, Mar, 23(3): 425-434.

• Bottone, FG, Baek SJ, Nixon, JB, and Eling, TE (2002). Diallyl Disulfide (DADS) Induces the Antitumorigenic NSAID-Activated Gene (NAG-1) by a p53-Dependent Mechanism in Human Colorectal HCT 116 Cells. J Nutr. Apr, 132(4):773-778.

• Kim, KS, Baek SJ, Flake, G, Loftin CD, Calvo BF, and Eling, TE (2002). Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue. Gastroenterology. May, 122(5):1388-1398.

• Baek SJ, Wilson L, Lee, CH, and Eling TE. (2002) Dual Function of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Inhibition of Cyclooxygenase and Induction of NSAID-Activated Gene. J Pharmacol Exp Ther. June, 301(3):1126-1131.

 

2001

• Kameda H, Risinger JI, Han BB, Baek SJ, Barrett JC, Abe T, Takeuchi T, Glasgow WC, Eling TE. (2001) Expression of gab1 lacking the pleckstrin homology domain is associated with neoplastic progression. Mol Cell Biol. 21(20): 6895-6905.

• Baek SJ, Kim KS, Nixon J, Wilson L, and Eling TE. (2001) Cyclooxygenase inhibitors regulate the expression of a TGF-b superfamily member that has pro-apoptotic and anti-tumorigenic activities. Mol Pharmacol. 59(4): 901-908.

• Ikawa H, Kameda H, Kamitani H, Baek SJ, Nixon JB, Hsi LC, and Eling TE. (2001) Effects of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells. Exp Cell Res. 267(1): 73-80.

• Baek SJ, Horowitz JM, and Eling TE. (2001) Molecular cloning and characterization of human anti-inflammatory drug-activated gene promoter: Basal transcription is mediated by Sp1 and Sp3. J Biol Chem. 276(36): 33384-33392.

• Kameda H, Risinger JI, Han B-B, Baek SJ, Barrett C, Glasgow WC, and Eling TE. (2001) Identification of epidermal growth factor receptor-Grb2-associated binder-1-SHP-2 complex formation and its functional loss during neoplastic cell progression. Cell Growth Differ. 12(6): 307-318.

• Fritsche E, Baek SJ, King, LM, Zeldin DC, Eling TE, and Bell DA (2001) Functional characterization of COX-2 polymorphisms. J Pharmacol Exp Ther. 299(2): 468-76.