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Comparative Gastroenterology

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BACKGROUND

A 14-year old female spayed American Domestic Shorthair Cat is presented to your clinic with a 2 day history of anorexia, bloody vomiting and loose stools. The cat had a chronic history of weight loss, lethargy and occasional vomiting. She had been diagnosed with lymphocytic-plasmacytic enteritis and Helicobacter infection on endoscopic biopsy, 2 weeks prior to presentation. Since than she had been treated with amoxicillin (22.0 mg/kg, PO, Q8h), omeprazole (1 mg/kg, PO, Q24h) and prednisone (1 mg/kg, PO, Q12h). There is no history of sneezing, coughing or straining to defecate. At presentation, the patient is underweight (5.1 lbs; 2.4 kg) and has an unkept hair coat. On physical examination, the cat is dehydrated (5 – 7%) and does not show pain on palpation of the abdomen. Further physical examination is not possible due to lack of patient cooperation. The CBC is within normal reference ranges and plasma biochemical panel shows a mild increase in BUN, creatinine, K+ and glucose. Serum T4 is within normal limits and serologic tests for FIP/FeLV/FIV are negative. Initial abdominal radiographs and ultrasound are unremarkable with the exception of bilaterally small kidneys. The cat is admitted to the hospital for supportive care and food is withheld due to the vomiting and IV fluids (Normosol + KCl) are administered. Sucralfate is added to the medication. The following day the cat appears to be more alert than at the time of admission, however a 1x2 cm firm, irregular mass is palpated in the right cranial abdomen, and the cat vomits after palpation. Right lateral (Image A) and ventrodorsal (Image B) abdominal radiographs are repeated.

  • What’s your diagnosis?
  • What other diagnostic tests would be helpful in determining the diagnosis?
  • What treatment(s) would be appropriate?
AUTHORS:

 

DIAGNOSIS

Right lateral (Image A) and VD (Image B see below with arrows) radiographs of the abdomen show an approximately 5 x 2.5 cm elongated well-defined soft tissue opacity within the ascending colon. The right kidney is small (approximately 1 x the length of L2) and the left kidney is at the lower limits of normal for size (approximately 2 x length of L2). Both kidneys show foci of mineralization. There are multifocal changes affecting the spine, which is considered incidental. Radiographic diagnosis: Intraluminal mass associated with the ascending colon. Intussusception is the primary differential diagnosis in light of the history and essentially unremarkable radiographic and ultrasonographic studies the day before. The possibility of unusual fecal material is considered far less likely. Renal changes are compatible with chronic renal disease.

Abdominal exploratory surgery was performed, and the presumptive diagnosis of ileocecocolic intussusception was confirmed. The intussusception was manually reduced and 2 segments of bowel were plicated to one another to prevent recurrence of intussusception. Full thickness biopsies of duodenum and jejunum were taken, which confirmed the previous diagnosis of chronic marked lymphocytic-plasmacytic enteritis. The cat was discharged on amoxicillin and omeprazole, and prednisone was added to the medication 10 days following surgery.

 

 

COMMENTS TO IMAGES

Image B: On the VD view there is a 5 x 2.5 cm intraluminal soft tissue mass associated with the ascending colon (arrows), which represents the intussusceptum. Small kidneys with mineralization are consistent with chronic renal disease. The changes associated with the spine are considered incidental.