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The University of Tennessee

The College of Veterinary Medicine

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Large Animal Clinical Sciences

RESEARCH

Center for Endocrine and Metabolism Research (CEMR)
http://www.vet.utk.edu/cemr/
The Center for Endocrine and Metabolism Research (CEMR) has been recently established at The University of Tennessee College of Veterinary Medicine (UTCVM) to foster collaborative work between researchers inside and outside of the college. This center is not a specific building or even a certain laboratory, but instead represents a collection of researchers that share common interests. We encourage researchers, veterinary practitioners, and clients to contact us for further information. 
Contact Dr. Nicholas Frank via e-mail at . 

Ultrasound Studies in Wound Healing
This project will correlate healing strength of surgical incision sites. This information will help to establish guidelines for returning a horse back to work after abdominal surgery. Dr. Blackford 

Evaluation of a Balanced Anesthetic Regimen in Horses
This study evaluates the effect of using a variety of drugs during anesthesia to provide analgesia and improve the outcome of the anesthesia. Over 100 horses have been studied and the results indicate that recovery from anesthesia can be improved by using a select anesthetic regimen. Drs. Doherty & Geiser

Effects of Prokinetic Drugs on Gastric Emptying in Horse
Ileus (lack of intestinal motility) is a common occurrence following surgery in the horse. This research investigates the effect of treatment with a variety of drugs in experimentally delayed gastric emptying in horses. The results will help the surgeon decide on the best drugs for use in the post-surgical horse. Drs. Doherty & Andrews

Wound Management Intervention
Often the wounds on animals are seen too late or are too contaminated which prevents suturing. Open wound management is being investigated by using several different treatments: collagen dressing, antibiotic impregnated beads, and regional limb perfusion. The results will help the clinician to choose the most appropriate treatment for a particular wound. Dr. Blackford

Creation of an Economic Model to Simulate the Return and Investment in Pregnancy Examinations at Weaning in Beef Brood Cows
The results of this study will help create an economic simulation model using readily available information from beef producers and to estimate the profit resulting from palpating beef brood cows for pregnancy at weaning. The model will also tailor the results of the economic simulation to individual beef producers. Dr. Rohrbach

Creation of a Simulation Model to Estimate the Optimum Age at Which to Cull Beef Cows
This model, using inputs from individual beef cow/calf producers, will maximize the profit decisions to cull beef brood cows. Dr. Rohrbach

Determination of the Effect of Infection with Bluetongue Virus (BTV) on Health and Productivity of Tennessee Beef Cattle
This study will compare the measures of health and production of cows infected with BTV. It will also compare the growth of BTV-infected calves with that of non-infected calves. Dr. Rohrbach

Test of a New Treatment to Reduce the Risk and Severity of Recurrent Episodes of Uveitis (Moon Blindness) in Horses
This study will investigate the use and merits of vaccines to provide protection against recurrent uveitis. An experimental vaccine will be studied to provide efficacy information. Dr. Rohrbach

The Etiopathogenesis (causes) of Interdigital Dermatitis in Cattle
Biopsies and cultures will be taken from cows with clinical signs of this disease to determine the cause. The results of the study will help determine the choice of antibiotic treatment and management methods to control interdigital dermatitis.
Dr. van Amstel

The Impact of Claw Trimming on Lameness and Milk Production in Dairy Cows
The effect of claw trimming will be assessed through the incidence of lameness and milk production over a 12 month period. These will be compared to an untrimmed control group. The results will provide information on the usefulness of claw trimming in dairy cows. Dr. van Amstel

Intranasal Protection Against Bovine Respiratory Syncytial Virus
The efficacy of intranasal administration of two bovine syncytial virus vaccines in healthy calves will be evaluated. Antibody response and adverse reactions will be monitored following extra-label vaccine use. The results will help in decision-making for use of vaccines in calf health management. Dr. Welborn

Reactivity of Bovine Vasculature to Ergovaline and Ergine of the Fescue
This is a study to determine how the toxins of fungus-infected fescue affect the blood vessels in the bovine. The results will help in treatment and prevention, including vaccine development, of the detrimental effects to cattle on fescue pastures. 
Drs. Oliver, Linnabary, & Schultz 

Assessment of Inflammatory and Immunologic Response of Cattle to Tall Fescue Toxins
This research will help us to understand the affect of fescue mycotoxins on the bovine's ability to react to disease and to develop immunity to diseases through exposure or vaccines. This research will help to clarify the immune response to cattle on fescue pastures and what management changes are necessary to prevent poor immune response. Drs. Oliver & Linnabary


Dog Bite Prevention