Education

• Doctorate of Philosophy (PhD) in Veterinary Clinical Science – Purdue University

• Doctorate of Veterinary Medicine (DVM) – Purdue University

Training

• Residency Large Animal Medicine – Purdue University

Board Certification

•  Diplomate – American College of Veterinary Internal Medicine (ACVIM)

Teaching

• Endocrine diseases of the horse

• Metabolic disorders of horses

• Metabolic disorders of ruminants

Clinical Interests

• Endocrinology, Metabolic Disorders, Neonatology, Geriatric Horse Medicine, Nutrition

Research Interests

• Laminitis, insulin resistance, equine metabolic syndrome

• Blood lipids, lipid metabolism, hyperlipemia, hepatic lipidosis, diabetes, obesity, equine Cushing’s disease, hypothyroidism, calcium disorders, neonatology, and nutrition.

Professional Societies

• American Veterinary Medical Association (AVMA)
  American College of Veterinary Internal Medicine (ACVIM)
  Equine Nutrition and Physiology Society (ENPS)

Peer Reviewed Publications

• Nadeau JA, Frank N, Valipe SR, et al. Blood lipid, glucose, and insulin concentrations in Morgan horses and Thoroughbreds. J Equine Vet Sci 2006; 26:401-405.
• Andrews FM, Frank N, Sommardahl C, et al. Effects of intravenously administrated omeprazole on gastric juice pH and gastric ulcer scores in adult horses. J Vet Intern Med 2006; 20:1202-1206.

• Frank N, Andrews FM, Sommardahl C, et al. Evaluation of the combined dexamethasone suppression / thyrotropin-releasing hormone (TRH) stimulation test for the diagnosis of pituitary pars intermedia dysfunction in horses. J Vet Intern Med 2006; 20:987-993.   

• Coffer NJ, Frank N, Elliott SB. Effects of dexamethasone and isoflupredone acetate on plasma potassium concentrations and other biochemical measurements in dairy cows in early lactation. Am J Vet Res 2006; 67:1244-1251.

• Frank N, Elliott SB, Brandt LE, et al. Physical characteristics, blood hormone concentrations, and plasma lipid concentrations in obese insulin resistant horses. J Am Vet Med Assoc 2006; 228:1383-1390.

• Frank N, Elliott SB, Allin SB, et al. Blood lipid concentrations and lipoprotein profiles in captive and wild American black bears (Ursus americanus). Am J Vet Res 2006; 67:335-341.

• Frank N, Andrews FM, Elliott SB, et al. Effects of dietary oils on the development of gastric ulcers in mares. Am J Vet Res 2005; 66:2006-2011.

• Frank N, Andrews FM, Elliott SB, et al. Effects of rice bran oil on plasma lipid concentrations, lipoprotein composition, and glucose dynamics in mares. J Anim Sci 2005; 83:2509-2518.

• Morandi F, Frank N, Avenell J, et al. Quantitative assessment of hepatic function using plasma time-activity curves of ^99mTc-Mebrofenin in healthy fed and feed-deprived horses. J Vet Intern Med 2005; 19:751-755.

• Eiler H, Frank N, Andrews FM, et al. Physiologic assessment of blood glucose homeostasis via combined intravenous glucose and insulin testing in horses. Am J Vet Res 2005; 66:1598-1604.     

• Frank N, Sommardahl C, Eiler H, et al. Effects of oral levothyroxine sodium on plasma lipid concentrations, very low density lipoprotein concentration and composition, and glucose dynamics in healthy adult mares. Am J Vet Res 2005; 66:1032-1038.

• Sommardahl C, Frank N, Elliott S, et al. Effects of oral levothyroxine sodium on serum thyroid hormone concentrations and responses to thyrotropin-releasing hormone (TRH) injection in healthy adult mares. Am J Vet Res 2005; 66:1025-1031.

• Sakamoto K, Kiupel M, Frank N, et al. Vertebral malformation, syringomyelia, and ventricular septal defect in a dromedary camel (Camelius dromedarius). J Vet Diagn Invest 2004; 16:337-340.

• Frank N, Sojka JE, Latour MA. Effect of hypothyroidism on the blood lipid response to higher dietary fat intake in mares. J Anim Sci 2004;82:2640-2646.

• Frank N, Sojka JE, Patterson BW, et al. Effect of hypothyroidism on kinetics of metabolism of very-low-density lipoprotein in mares.  Am J Vet Res 2003;64:1052-1058.

• Frank N, Sojka JE, Latour MA. Effects of hypothyroidism and withholding of feed on plasma lipid concentrations, concentration and composition of very-low-density lipoprotein, and plasma lipase activity in horses. Am J Vet Res 2003; 64:823-828.

• Frank N, Sojka JE, Latour MA. Effect of withholding feed on concentrations and composition of plasma very low density lipoprotein and serum nonesterified fatty acids in horses. Am J Vet Res 2002; 63:1018-1021.

• Braun CM, Frank N, Latour MA. The circulating levels of lipoproteins in embryos and newly hatched ducklings change with parental age. Biol Neonate 2002; 82:128-133.

• Morisset S, Hawkins JF, Frank N, et al. Surgical management of a ureteral defect with ureterorrhaphy of ureteritis with ureteroneocystostomy in a foal. J Am Vet Med Assoc 2002; 220:354-358.

• Hawkins JF, Frank N, Sojka JE, et al. Fistulation of the auditory tube diverticulum (guttural pouch) with a neodymium:yttrium-aluminum-garnet laser for treatment of chronic empyema in two horses. J Am Vet Med Assoc 2001; 216:405-407.

• Al-Rawashdeh, OF, Al-Ani FK, Sharrif LA, Al-Qudah KM, Al-Hami Y, Frank N. A survey of camel (Camelus dromedarius) diseases in Jordan. J Zoo Wildl Med 2000; 31:335–338.

• Kiupel M, Frank N, Stevenson GW, et al. Intrapelvic hemangiosarcoma in a horse. J Vet Diagn Invest 2000; 12:91-95.

• Frank N, Sojka JE, Latour MA, et al. Effect of hypothyroidism on blood lipid concentrations in horses. Am J Vet Res 1999; 60:730-733.

• Frank N, Fishman CE, Gebhart CJ, Levy M. Lawsonia intracellularis proliferative enteropathy in a weanling foal. Equine Vet J 1998; 30:549-552.

• Frank N, Couetil LL, Clarke KA. Listeria monocytogenes and Escherichia coli septicemia and meningoencephalitis in a 7-day-old llama. Can Vet J 1998; 39:100-102.

• Frank N, Hawkins JF, Couetil LL, Raymond JT. Primary hyperparathyroidism with osteodystrophia fibrosa of the facial bones in a pony. J Am Vet Med Assoc 1998; 212:84-86.

Other Publications

• Frank N. Serum chemistry analysis prior to anesthesia. In: Doherty T, Valverde A eds. Manual of Equine Anaesthesia and Analgesia, Oxford, UK, Blackwell Publishing Ltd (in press).

• Frank N, Sojka JE, Messer NT.  Equine thyroid dysfunction. Vet Clin N Am Equine Pract  2002;18:1-15.

• Frank N.  Hyperlipidemia. In: Brown CM, Bertone JJ eds. The 5-Minute Veterinary Consult – Equine, Philadelphia, Lippincott Williams & Wilkins, 2002:526-529.

Abstracts & Proceedings

• Frank N, Dhar M, Elliott SB, et al. Effects of long-term levothyroxine administration on adipose and skeletal muscle tissue glucose transporter gene expression in mares. American College of Veterinary Internal Medicine 24^th Annual 2006 Forum, Louisville, KY. June 2006. Published in J Vet Intern Med 2006; 20:743.

• Coffer N, Frank N, Elliott SB, et al. Effects of dexamethasone and isoflupredone acetate on milk production and serum biochemistry values in dairy cows. American College of Veterinary Internal Medicine 23^rd Annual 2005 Forum, Baltimore, MD. June 2005. Published in J Vet Intern Med 2005; 19:411.

• Frank N. Obesity and Insulin Resistance in Horses.  Published in the proceedings of the American College of Veterinary Internal Medicine 23^rd Annual 2005 Forum, Baltimore, MD. June 2005.

• Frank N, Sommardahl C, Boston R, et al. Effects of oral levothyroxine on glucose dynamics in mares. American College of Veterinary Internal Medicine 22^nd Annual Forum, Minneapolis. June 2004. Published in J Vet Intern Med 2004; 17:414

• Sommardahl C, Frank N, Elliott S, et al. Effects of oral levothyroxine on serum concentrations of thyroid hormones and thyroid stimulating hormone (TSH) in mares. American College of Veterinary Internal Medicine 22^nd Annual Forum, Minneapolis. June 2004. Published in J Vet Intern Med 2004; 17:414

• Eiler H, Frank N, Andrews FM, et al. Combined intravenous insulin and glucose test: A method for physiological assessment of glucose homeostasis in the horse. American College of Veterinary Internal Medicine 22^nd Annual Forum, Minneapolis. June 2004. Published in J Vet Intern Med 2004; 17:414-415.

• Morandi F, Frank N, Avenell J, Daniel GB. Evaluation  of  plasma time-activity curves of 99mTc-mebrofenin for evaluation  of  hepatic  function in normal non-fasted and fasted horses. European Association of Veterinary Diagnostic Imaging Annual Scientific Meeti

• Andrews FM, Frank N, Sommardahl C, et al. Diagnostic value of a combined dexamethasone suppression/thyrotropin-releasing hormone stimulation in equine Cushing’s disease. December 2004. Published in Proceedings. 50^th Annual American Association of Equine Practitioners Convention; 50:338-340.

• Frank N, Sojka JE, Latour MA. Effect of fasting on blood lipid concentrations in horses.  International Animal Agriculture and Food Science Conference, Indianapolis. July 2001. Published in J Anim Sci 2001; 79, Suppl. 1: 208-209

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